Market
Top Selling Drugs
Top 10 by global sales · Revenue in billions USD
Oncology
Metabolic
Immunology
Hematology / CV
Infectious Disease
$0B
$10B
$20B
$30B
$40B
Keytrudapembrolizumab~2028
Mounjarotirzepatide~2036
Ozempicsemaglutide~2031
Dupixentdupilumab~2034
Skyrizirisankizumab~2033
Eliquisapixaban~2026
Darzalexdaratumumab~2029
Biktarvybictegravir~2033
Zepboundtirzepatide~2036
Wegovysemaglutide~2031
Mounjaro + Zepbound (tirzepatide):$36.5B
Ozempic + Wegovy (semaglutide):$31.2B
Source: Nature Reviews Drug Discovery — Top drugs by sales in 2025
Top Selling Companies
Top 10 pharma companies by prescription drug sales · Revenue in billions USD
Eli Lilly
Johnson & Johnson
AbbVie
Roche
AstraZeneca
Merck & Co.
Novartis
Pfizer
Sanofi
Bristol Myers Squibb
$80B
$60B
$40B
$20B
$0B
Eli Lilly
Johnson & Johnson
AbbVie
Roche
AstraZeneca
Merck & Co.
Novartis
Pfizer
Sanofi
Bristol Myers Squibb
Source: Nature Reviews Drug Discovery — Top companies by sales in 2025